10,955 research outputs found

    Electromagnetic radiation of baryons containing two heavy quarks

    Get PDF
    The two heavy quarks in a baryon which contains two heavy quarks and a light one, can constitute a scalar or axial vector diquark. We study electromagnetic radiations of such baryons, (i) \Xi_{(bc)_1} -> \Xi_{(bc)_0}+\gamma, (ii) \Xi_{(bc)_1}^* -> \Xi_{(bc)_0}+\gamma, (iii) \Xi_{(bc)_0}^{**}(1/2, l=1) -> \Xi_{(bc)_0}+\gamma, (iv) \Xi_{(bc)_0}^{**}(3/2, l=1) -> \Xi_{(bc)_0}+\gamma and (v) \Xi_{(bc)_0}^{**}(3/2, l=2) -> \Xi_{(bc)_0}+\gamma, where \Xi_{(bc)_{0(1)}}, \Xi^*_{(bc)_1} are S-wave bound states of a heavy scalar or axial vector diquark and a light quark, and \Xi_{(bc)_0}^{**}(l is bigger than 1) are P- or D-wave bound states of a heavy scalar diquark and a light quark. Analysis indicates that these processes can be attributed into two categories and the physical mechanisms which are responsible for them are completely distinct. Measurements can provide a good judgment for the diquark structure and better understanding of the physical picture.Comment: 15 pages, Late

    Longitudinal Optogenetic Motor Mapping Revealed Structural and Functional Impairments and Enhanced Corticorubral Projection after Contusive Spinal Cord Injury in Mice

    Get PDF
    Current evaluation of impairment and repair after spinal cord injury (SCI) is largely dependent on behavioral assessment and histological analysis of injured tissue and pathways. Here, we evaluated whether transcranial optogenetic mapping of motor cortex could reflect longitudinal structural and functional damage and recovery after SCI. In Thy1-Channelrhodopsin2 transgenic mice, repeated motor mappings were made by recording optogenetically evoked electromyograms (EMGs) of a hindlimb at baseline and 1 day and 2, 4, and 6 weeks after mild, moderate, and severe spinal cord contusion. Injuries caused initial decreases in EMG amplitude, losses of motor map, and subsequent partial recoveries, all of which corresponded to injury severity. Reductions in map size were positively correlated with motor performance, as measured by Basso Mouse Scale, rota-rod, and grid walk tests, at different time points, as well as with lesion area at spinal cord epicenter at 6 weeks post-SCI. Retrograde tracing with Fluoro-Gold showed decreased numbers of cortico- and rubrospinal neurons, with the latter being negatively correlated with motor map size. Combined retro- and anterograde tracing and immunostaining revealed more neurons activated in red nucleus by cortical stimulation and enhanced corticorubral axons and synapses in red nucleus after SCI. Electrophysiological recordings showed lower threshold and higher amplitude of corticorubral synaptic response after SCI. We conclude that transcranial optogenetic motor mapping is sensitive and efficient for longitudinal evaluation of impairment and plasticity of SCI, and that spinal cord contusion induces stronger anatomical and functional corticorubral connection that may contribute to spontaneous recovery of motor function

    Antiviral activity of interleukin-11 as a response to porcine epidemic diarrhea virus infection

    Get PDF
    International audienceAbstractInterleukin-11 (IL-11), a well-known anti-inflammatory factor, provides protection from intestinal epithelium damage caused by physical or chemical factors. However, little is known of the role of IL-11 during viral infections. In this study, IL-11 expression at mRNA and protein levels were found to be high in Vero cells and the jejunum of piglets during porcine epidemic diarrhea virus (PEDV) infection, while IL-11 expression was found to be positively correlated with the level of viral infection. Pretreatment with recombinant porcine IL-11 (pIL-11) was found to suppress PEDV replication in Vero E6 cells, while IL-11 knockdown promoted viral infection. Furthermore, pIL-11 was found to inhibit viral infection by preventing PEDV-mediated apoptosis of cells by activating the IL-11/STAT3 signaling pathway. Conversely, application of a STAT3 phosphorylation inhibitor significantly antagonized the anti-apoptosis function of pIL-11 and counteracted its inhibition of PEDV. Our data suggest that IL-11 is a newfound PEDV-inducible cytokine, and its production enhances the anti-apoptosis ability of epithelial cells against PEDV infection. The potential of IL-11 to be used as a novel therapeutic against devastating viral diarrhea in piglets deserves more attention and study

    Novel MARG-Sensor Orientation Estimation Algorithm Using Fast Kalman Filter

    Get PDF
    Orientation estimation from magnetic, angular rate, and gravity (MARG) sensor array is a key problem in mechatronic-related applications. This paper proposes a new method in which a quaternion-based Kalman filter scheme is designed. The quaternion kinematic equation is employed as the process model. With our previous contributions, we establish the measurement model of attitude quaternion from accelerometer and magnetometer, which is later proved to be the fastest (computationally) one among representative attitude determination algorithms of such sensor combination. Variance analysis is later given enabling the optimal updating of the proposed filter. The algorithm is implemented on real-world hardware where experiments are carried out to reveal the advantages of the proposed method with respect to conventional ones. The proposed approach is also validated on an unmanned aerial vehicle during a real flight. Results show that the proposed one is faster than any other Kalman-based ones and even faster than some complementary ones while the attitude estimation accuracy is maintained

    The Extremely Luminous Quasar Survey (ELQS) in the SDSS footprint I.: Infrared Based Candidate Selection

    Full text link
    Studies of the most luminous quasars at high redshift directly probe the evolution of the most massive black holes in the early Universe and their connection to massive galaxy formation. However, extremely luminous quasars at high redshift are very rare objects. Only wide area surveys have a chance to constrain their population. The Sloan Digital Sky Survey (SDSS) has so far provided the most widely adopted measurements of the quasar luminosity function (QLF) at z>3z>3. However, a careful re-examination of the SDSS quasar sample revealed that the SDSS quasar selection is in fact missing a significant fraction of z≳3z\gtrsim3 quasars at the brightest end. We have identified the purely optical color selection of SDSS, where quasars at these redshifts are strongly contaminated by late-type dwarfs, and the spectroscopic incompleteness of the SDSS footprint as the main reasons. Therefore we have designed the Extremely Luminous Quasar Survey (ELQS), based on a novel near-infrared JKW2 color cut using WISE AllWISE and 2MASS all-sky photometry, to yield high completeness for very bright (mi<18.0m_{\rm{i}} < 18.0) quasars in the redshift range of 3.0≤z≤5.03.0\leq z\leq5.0. It effectively uses random forest machine-learning algorithms on SDSS and WISE photometry for quasar-star classification and photometric redshift estimation. The ELQS will spectroscopically follow-up ∼230\sim 230 new quasar candidates in an area of ∼12000 deg2\sim12000\,\rm{deg}^2 in the SDSS footprint, to obtain a well-defined and complete quasars sample for an accurate measurement of the bright-end quasar luminosity function at 3.0≤z≤5.03.0\leq z\leq5.0. In this paper we present the quasar selection algorithm and the quasar candidate catalog.Comment: 16 pages, 8 figures, 9 tables; ApJ in pres
    • …
    corecore